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Results from Expanded Access Programs: A Review of Academic Literature
Tobias B. Polak, David G J Cucchi, Jasmin Schelhaas, Syed S Ahmed, Naima Khoshnaw, Joost van Rosmalen, Carin A Uyl-de Groot
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Results from Expanded Access Programs: A Review of Academic Literature
Results from Expanded Access Programs: A Review of Academic Literature
BACKGROUND: Although expanded access is an increasingly used pathway for patients to access investigational medicine, little is known …
Tobias B. Polak, David G. J. Cucchi, Jasmin Schelhaas, Syed S. Ahmed, Naima Khoshnaw, Joost van Rosmalen, Carin A. Uyl – de Groot
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The Ethics of Expanded Access Research
This Viewpoint discusses the benefits of expanded access research, the usefulness of expanded access data, the issues surrounding cost …
Tobias Boy Polak, Holly Fernandez Lynch
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Generating Evidence from Expanded Access Use of Rare Disease Medicines: Challenges and Recommendations
Patients with rare diseases often have limited or no options for approved treatments or participation in clinical trials. In such …
Tobias B. Polak, David G. J. Cucchi, Joost van Rosmalen, Carin A. Uyl – de Groot, Jonathan J. Darrow
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The DRUG Access Protocol: Access Inequality and European Harmonisation
Tobias B Polak, David G J Cucchi, Joost van Rosmalen, Carin A Uyl-de Groot
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Incremental Benefits of Novel Pharmaceuticals in the UK: A Cross-Sectional Analysis of NICE Technology Appraisals from 2010 to 2020
Tobias B Polak, David GJ Cucchi, Jonathan J Darrow, Matthijs M Versteegh
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Real-World Data from Expanded Access Programmes in Health Technology Assessments: A Review of NICE Technology Appraisals
Tobias B Polak, David GJ Cucchi, Joost van Rosmalen, Carin A Uyl-de Groot
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The Predictive Value of a Positive Phase II ASH Abstract for Peer-Reviewed Publication and Progression to Phase III
David GJ J. Cucchi, Tobias B. Polak, Gert J. Ossenkoppele, Jacob M. Rowe, Elihu H. Estey
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The Wider Perspective: Twenty Years of Clinical Trials in Myelodysplastic Syndromes
Carolien Duetz, David G. J. Cucchi, Tobias B. Polak, Jeroen J. W. M. Janssen, Gert J. Ossenkoppele, Elihu H. Estey, Arjan A. Loosdrecht
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Financial Considerations in Expanded Access Policy for Gene Therapies: A Tough Nut to Crack?
Tobias B. Polak, Eline M. Bunnik
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